Formulation development of herbal anti acne gel
Kushwaha Ritu*, Kapil Malviya, Lavakesh Kumar Omray
ONLINE ISSN : 2456-8244ABSTRACT
Antibiotics have been used to treat acne vulgaris. However, antibiotic resistance has been increasing
in prevalence within the dermatologic setting. The development of antibiotic resistance includes the
specific nature of the relationship of bacteria to antibiotics, how the antibacterial is used, host
characteristics, and environmental factors. Natural remedies are more acceptable in the belief that
they are safer with fewer side effects than the synthetic ones. Herbal formulations have growing
demand in the world market. It is a very good attempt to establish the herbal gel containing hydroalcoholic
extract of Rhizome of Curcuma longa, Curcuma Caesia and Curcuma Amada. This study revealed
that the developed single herbal formulation F3 was comparatively better than other formulation.
KEYWORDS
Herbal, Anti-Acne, Curcuma longa, Curcuma Caesia, Curcuma Amada
DOI
REFERENCES
1. Balammal G, Sekar BM, Reddy JP.
Analysis of Herbal Medicines by
Modern Chromatographic Techniques. International Journal of Preclinical and
Pharmaceutical Research 2012;
3(1):50-63.
2. Pal KS, Shukla Y. Herbal Medicine:
Current Status and the Future. Asian
Pacific J Cancer Prev 2003; 4:281-288.
3. Kashaw V, Nema AK, Agarwal A.
Hepatoprotective Prospective of
Herbal Drugs and Their Vesicular
Carriers– A Review. International
Journal of Research in Pharmaceutical
and Biomedical Sciences 2011; 2(2).
4. Prabhu TP, Panneerselvam P, kumar
RV, Atlee WC, Subramanian SB. Antiinflammatory,
anti arthritis and
analgesic effect of ethanolic extract of
whole plant of Merremia emarginata
Burm.F. Central European Journal of
Experimental Biology. 2012; 1(3):94-
99.
5. Patel P, Patel D, Patel N.
Experimental investigation of antirheumatoid
activity of Pleurotus
sajorcaju in adjuvant -induced arthritic
rats. Chinese Journal of Natural
Medicines. 2012; 10(4):269-274.
6. Agarwal P, Fatima A Singh PP. Herbal
Medicine Scenario in India and
European Countries, Journal of
Pharmacognosy and Phytochemistry.
2012; 1(4).
7. Gautam RK, Singh D, Nainwani R.
Medicinal Plants having Anti-arthritic Potential: A Review, Int. J. Pharm. Sci.
Rev. Res. 2013; 19(1):96-102.
8. Patil RB, Vora SR, Pillai MM.
Protective effect of Spermatogenic
activity of Withania somnifera
(Ashwagandha) in galactose stressed
mice, Annals of Biological Research.
2012; 3(8):4159-4165.
(http://scholarsresearchlibrary.com/ar
chive.html).
9. Brown HM, Christie AB, Colin EJ.
Glycyrrhetinc acid hydrogensuccinate
(disodium) salt, a new
antiinflammatory compound, Lancet.
1959;2:492.
10. Adami E, Marzzi EU, Turba C. Arch
Int Pharmaco dyn Tuer 1964: 147:113.
11. Kamboj VP. Herbal medicine, Current
science. 2000; 78(1).
12. Partap S, Kumar A, Sharma NK, Jha
KK. Luffa Cylindrica: An important
medicinal plant, J. Nat. Prod. Plant
Resour 2012; 2 (1):127-134.
13. Verma S, Singh SP. Current and future
status of herbal medicines, Veterinary
World. 2008; 1(11):347-350.
14. Padmawar A, Bhadoria U.
Phytochemical investigation and
comparative evaluation of in vitro free
radical scavenging activity of Triphala
& Curcumin. Asian Journal of
Pharmacy and Medical Science. 2011;
1(1): 9-12.
15. Ampofo AJ, Andoh A, Tetteh W,
Bello M. Microbiological Profile of
Some Ghanaian Herbal Preparations-
Safety Issues and Implications for the
Health Professions, Open Journal of
Medical Microbiology. 2012; 2:121-
130.
16. Mosihuzzaman M, Choudhary MI.
Protocols on Safety, Efficacy,
Standardization, and Documentation
of Herbal Medicine, Pure Appl. Chem.
2008; 80(10):2195–2230.
17. Rukangira E. The African Herbal
Industry: Constraints and Challenges,
proc: “The natural Products and
Cosmeceutcals
2001conference”.Africa. 2000: 1-20.
18. Kamboj A. Analytical Evaluation of
Herbal Drugs, Drug Discovery
Research in Pharmacognosy, 2012;
3:23- 55.
19. Zatz JL, Kushla GP: Gels. In:
Lieberman HA., Rieger MM and
Banker GS. Pharmaceutical dosage
form: Disperse system, 2nd ed. New
York: Marcel Dekker; 2005:399-421.
20. Niyaz BB, Kalyani P, Divakar G:
Formulation and evaluation of gel
containing fluconazole antifungal
agent. International Journal of Drug
Development and Research. 2011;
3(4): 109-128.