In the present article a few pyrimidinethione derivatives are synthesized in a two step procedure using microwave radiation. The compounds are screened for antibacterial activity against four bacterial species. The results revealed that the compounds are obtained in good yields as compared to the conventional method of synthesis and the time required for the completion of the reaction was considerably less. All the compounds exhibited antibacterial potential against the gram negative and gram positive bacteria tested

Pyrmidinethione, antimicrobial, microwave assisted synthesis, chalcone

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